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Acne Gene Expression

Dec 6, 2018
2 min read

Updated: Mar 5, 2025



If you recognize that your lifestyle choices could change the expression of your genes without changing your DNA, would you make better life choices?


The word “epigenetic” means “in addition to changes in genetic sequence.” This is exciting because it means that certain conditions are required for a specific gene to be turned on and therefore activated. That's right! Genes can be switched on and off.


For instance, even if you are genetically predisposed to have lung disease, it doesn’t mean you will. You have to create the conditions for this condition to thrive, by, for example, smoking a pack a day.


The same is true for acne and other skin problems. Maybe you are genetically coded to be able to express the acne gene. However, certain conditions must be satisfied for acne to appear. These conditions can differ for all individuals, so custom skin care and personalized health coaching is essential. No one size fits all!


However, one underlying cause for acne is inflammation. Many factors can induce inflammation, but most are triggered by lifestyle choices, which means you have the POWER to make better choices. Our acne coaching program can provide proven lifestyle tips to prevent/treat acne.


Did you know that only about 5% or less of genetic mutations result in disease – we are left with 95% of genes that can be influenced by other factors, like chronic stress.

Another factor that modulates gene expression is diet. A diet composed of high-refined carbs can promote high blood sugar, damaging your DNA. While other types of foods, such as cruciferous vegetables, can slow or even reverse DNA damage.


Chronic stress is another factor that is detrimental to the over-expression of over 700 genes, according to recent studies. Stress reduction, meditation, and even positivity can turn off the expression of pro-inflammatory genes, resulting in inflammation reduction. The epigenetic benefits during these studies were experienced almost immediately.


As a result of this exciting discovery, we can now understand why some individuals get acne later in life. Genes can be switched on and off. Acne is genetic for "true acne" as it continues throughout life. It does not stop after teenage years. However, acne can be induced by diet, supplementation, and lifestyle choices. Therefore, our choices are powerful in the way our genes are expressed. If you have acne-prone skin, it is best to learn to make the best choices to silence these pro-inflammatory genes.


Would you agree?


If you need help treating your acne, be sure to book your consultation online or in-person to get to the root-cause. We understand acne and how to balance the body to get clear skin!

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Resources:


DNA Methylation Society (international) http://www.dnamethsoc.com/main.htm

Epigenome Network of Excellence (Europe) http://www.epigenome-noe.net

Human Epigenome Project (Europe) http://www.epigenome.org

http://www.landesbioscience.com/journals/epigenetics/

http://igc.otago.ac.nz/home.html

http://www.geneimprint.com/databases/?c=clist

http://www.mgu.har.mrc.ac.uk/research/imprinting/

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The information provided on this website and through Integrative Aesthetics Boston is intended for general educational and informational purposes only and should not be considered individualized medical advice. Integrative Aesthetics Boston is a functional dermatology and integrative skincare practice led by a licensed Nurse Practitioner. Clinical evaluation, diagnosis, treatment, prescriptions, laboratory testing, skincare recommendations, procedures, and other services are provided only when appropriate within an established clinician-patient relationship and within the practitioner’s professional scope of practice. Website content does not establish a clinician-patient relationship and should not be used as a substitute for individualized evaluation by a qualified healthcare professional. If you have, or suspect that you have, a medical condition, please seek appropriate medical care. Do not start, stop, or change medications, supplements, nutrition, or other aspects of your medical care without guidance from a qualified healthcare professional. Integrative Aesthetics Boston may collaborate with or refer patients to dermatologists, primary care providers, and other qualified healthcare professionals when clinically appropriate. Individual results vary and cannot be guaranteed. Integrative Aesthetics Boston does not provide emergency or urgent-care services. If you are experiencing a medical emergency or severe or rapidly worsening symptoms, call 911 or seek immediate care through an emergency department or appropriate urgent-care provider. Statements regarding dietary supplements have not been evaluated by the U.S. Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent disease.

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